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ThioEthix™ -Injection

Thiocolchicoside Injection 

PACKING SIZE / TYPE

4mg/2ml

Summary

ThioEthix™ is used to provide relief from rigidity, tension and stiffness in muscles that may occur due to various conditions affecting your nervous system. It is also used in combination with other medicines to treat joint pains.

Thiocolchicoside works by blocking certain receptors in your brain that cause pain, stiffness and swelling. Thiocolchicoside comes in oral (tablet and capsule) and injection dosage forms. Your doctor will decide the dosage form based on the severity of the pain. Thiocolchicoside has some common side effects like diarrhoea, stomach pain, nausea and sleepiness. This medicine may also cause dizziness. Do not drive vehicles or do anything requiring concentration until you know how it affects you. If any of these side effects do not resolve with time or get worse, seek a doctor's consultation at the earliest. Avoid taking this medicine if you are allergic to it.

Thiocolchicoside should be taken with or immediately after food to avoid an upset stomach. Thiocolchicoside injection should be given in the hospital setting by specialized healthcare professionals. Your doctor will prescribe you a lower dose at first and adjust it to a higher dose if there is no improvement in your condition. Do not stop taking this medicine on your own and avoid missing the dose. Consult your doctor if you suspect an overdose of this medicine.

Thiocolchicoside is safe for you if you can share your entire medical and medication history with your doctor. Inform your doctor if you are pregnant, planning a pregnancy or are breastfeeding before taking this medicine. This medicine should only be used in adolescents and adults above 16 years of age.

Side Effects

Major & minor side effects for Thiocolchicoside

  • Itching and skin rash
  • Swelling of face, lips, eyelids, tongue, hands and feet 
  • Fainting and drowsiness
  • Nausea and Vomiting
  • Diarrhoea
  • Yellowing of skin and eyes
  • Photosensitivity
  • Dry mouth
  • Headache
  • Stomach pain

Usage

What is it prescribed for?

  • Muscle spasm

    Thiocolchicoside is used to relieve muscle spasms and pain, thus improving muscle movement. This includes back pain, neck pain, etc.

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Concerns

Commonly asked questions

  • Onset of action

    The time Thiocolchicoside takes to show its effect is subject to vary based on the strength and the form in which the medicine is taken.

  • Duration of effect

    The amount of time for which ThioEthix™ remains effective is subject to vary based on the strength and form in which the medicine is taken.

  • Safe with alcohol?

    Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

  • Is it habit forming?

    Thiocolchicoside has no habit-forming tendency.

  • Usage in pregnancy?

    Thiocolchicoside is not recommended for use in pregnant women as it affects your foetus.

  • Usage while breast-feeding?

    Thiocolchicoside is not recommended for use in breastfeeding women. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

When not to use?

Allergy

It is recommended to avoid using ThioEthix™ if you are allergic to this medicine. Seek medical attention if you see symptoms such as skin rash, swelling ( of your face, lips, tongue, etc.), breathing difficulty, etc.

Warnings

Warnings for special population

Pregnancy

Thiocolchicoside is not recommended for use in pregnant women as it affects your foetus.

Breast-feeding

Thiocolchicoside is not recommended for use in breastfeeding women. Your doctor may advise you to discontinue breastfeeding or to discontinue the drug based on your clinical condition.

General warnings

Other medicines

Thiocolchicoside may interact with any medicine you are taking. Let your doctor know all your current medicines to avoid the chances of possible interaction with this medicine.

Kidney disease

Thiocolchicoside should be used with caution in the presence of kidney diseases due to the increased risk of worsening of kidneys.

Driving or Operating machinery

Thiocolchicoside may cause dizziness and a decrease in blood pressure. Avoid performing any activities that require high mental alertness like driving vehicles or operating machines if you experience it until you know how this medicine affects you.

Use in children

Thiocolchicoside is not recommended for use in children and adolescents less than 16 years of age.

Impairment of fertility

The use of Thiocolchicoside may cause impairment of fertility in men. Discuss all the risks and benefits with your doctor before taking this medicine.

Dosage

Missed Dose

Oral: If you missed a dose of ThioEthix™, take it as soon as you remember. If the next dose timing is near, skip the missed dose. Take your next dose at your usual time. Do not double the dose. Injection: Since Thiocolchicoside is given by a healthcare professional, the likelihood of missing a dose is low.

Overdose

Oral: Never take Thiocolchicoside more than the prescribed dose. If you suspect that you might have taken an overdose of this medicine, go to the emergency department of your local hospital. Injection: Since Thiocolchicoside is given by a healthcare professional, the likelihood of an overdose is low

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

CNS depressants

Other muscle relaxants

Disease interactions

Liver Disease

Thiocolchicoside should be used with caution as it may damage your liver. Inform your doctor if you experience stomach pain, nausea, yellowing of skin or eyes, dark coloured urine, etc.

Seizures

ThioEthix™ should be used with caution if there are seizures (fits) or in those with risk of seizures.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Oral: Take Thiocolchicoside tablet/capsule with or after food or a glass of milk. It may cause dizziness or sleepiness. Do not drive vehicles or do anything requiring concentration until you know how it affects you.

Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness. Do not take this medicine for a longer duration than recommended. Do not open, crush or chew the medicine in your mouth.

Injection: Thiocolchicoside should be given in the hospital setting by specialized healthcare professionals.

Other Details

Miscelleneous

To be taken after food

To be taken as instructed by doctor

May cause sleepiness

How it works

Thiocolchicoside works by interacting with certain specific receptors in the central nervous system (brain). It prevents muscle contractions and relieves muscle cramps.

Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Muscle relaxants

Schedule

Schedule H

References

Ema.europa.eu. 2021. [online] Available at: < [Accessed 1 September 2021].

https://www.ema.europa.eu/en/documents/referral/thiocolchicoside-article-31-referral-annex-iii_en.pdf>

Iasispharma.com. 2021. [online] Available at: < [Accessed 1 September 2021].

https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf>

Sanofi.in. 2021. [online] Available at: < [Accessed 15 September 2021].

https://www.sanofi.in/-/media/Project/One-Sanofi-Web/Websites/Asia-Pacific/Sanofi-IN/Home/science-and-innovation/for-healthcare-professionals/product-information/Myoril.pdf?la=en>

Iasispharma.com. 2021. [online] Available at: < [Accessed 15 September 2021].

https://iasispharma.com/wp-content/uploads/pdf/RELIEF_PIL_ENG.pdf>

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