ETHRAZOLE- 100 Capsule

10x10 Alu Alu Pack

ETHRAZOLE- 100 Capsule is an antifungal medicine used in the treatment of fungal infections in various parts of your body like the lungs, nails, mouth, throat, etc. It works by preventing the growth of fungi that are responsible for causing the infections.

ETHRAZOLE- 100 Capsule may show some side effects such as diarrhoea, nausea, stomach pain, bloating, dizziness, fatigue, headache, menstrual problems, etc. If you notice any allergic reactions like a skin rash, tingling sensation in your arms and legs, difficulty in breathing, or swelling of your face, lips, tongue, or neck, seek emergency medical attention.

ETHRAZOLE- 100 Capsule is recommended to be taken with food and plenty of water to ensure maximum absorption. Take it exactly as prescribed by your doctor. Even if your symptoms are relieved after a few days, do not stop taking this medication without consulting your doctor first. Sudden discontinuation may cause your infection to reappear and become resistant to further treatment. Consult your doctor if you do not notice any changes in your condition.

ETHRAZOLE- 100 Capsule is not recommended if you have a history of heart failure. Inform your doctor if you have any other medical conditions, or if you are taking any medications. Avoid taking this medicine if you are pregnant, especially in the first trimester as it may cause harm to your foetus. If you are breastfeeding, take this medicine only after your doctor's recommendation.

Major & minor side effects for ETHRAZOLE- 100 Capsule

• Diarrhoea
• Fever
• Heartburn
• Gas or bloating
• Sore or bleeding gums
• Decreased sexual urge
• Constipation
• Dizziness
• Nervousness
• Blurred vision
• Frequent urination
• Ringing in ears
• Nausea
• Stomach pain
• Problem in menstrual period
• Headache
• Fatigue

What is it prescribed for?

Blastomycosis

Blastomycosis is a fungal infection that can affect your lungs and also other parts of the body such as skin, bones, and joints. This condition is mostly asymptomatic (does not show symptoms) in the early stages, and when the infection becomes severe, it shows symptoms like night sweats, fever, cough, weight loss, chest pain, tiredness, etc. ETHRAZOLE- 100 Capsule slows down the growth of this fungus and prevents it from spreading, thus it helps in treating the condition.

Histoplasmosis

Histoplasmosis is a fungal infection that primarily affects your lungs. This condition may resolve on its own, but you will need treatment if the condition is severe. ETHRAZOLE- 100 Capsule is used to treat this condition by preventing fungal growth.

Invasive Aspergillosis

Invasive Aspergillosis is a fungal infection that mainly affects the lungs and spreads to other body parts like the brain, heart, kidney and skin. This infection may become life-threatening if you have a compromised immune system (immune system become weak due to certain medicines or diseases) or other underlying conditions. ETHRAZOLE- 100 Capsule slows down the spread of this fungus and thus helps in treating the condition.

Onychomycosis

Onychomycosis is a fungal infection in the fingernail and toenail. It is characterized by nail discolouration, ragged or crumbly nails, etc. ETHRAZOLE- 100 Capsule  helps prevent the spread of infection by reducing the growth of fungi.

Vulvovaginal Candidiasis

Vulvovaginal candidiasis is a fungal infection in the vagina that causes itching and white discharge. ETHRAZOLE- 100 Capsule helps in treating its symptoms and reduces the growth of the fungus.

Pityriasis versicolor

Pityriasis Versicolor is a fungal infection that affects the skin and leads to small flaky, discoloured patches on your chest and back. ETHRAZOLE- 100 Capsule works by killing fungus and preventing their growth. This relieves the different symptoms caused by the infection and speeds up the healing process.

 Dermatophytoses

Dermatophytoses is the infection caused by a fungus that affects your skin, nails or scalp. ETHRAZOLE- 100 Capsule stops the growth of fungus and helps in treating its symptoms like itchiness and rashes.

Oral candidiasis

Oral candidiasis is a fungal infection that is seen in the mouth. This condition is characterised by white lesions on the tongue and inner cheeks. ETHRAZOLE- 100 Capsule reduces these white lesions by preventing the growth of fungus.

How long does it take for this medicine to take effect?

The time taken by ETHZOLE-100 Capsule to show its effect is not clinically known. However, you need to take this medicine for a few months to see improvement in your infection.

How long do the effects of this medicine last?

The time for which ETHZOLE-100 Capsule remains in your body is around 6 days.

Is it safe to consume alcohol while taking this medicine?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?

No habit-forming tendencies were reported for ETHZOLE-100 Capsule.

Can this medicine be taken during pregnancy?

ETHZOLE-100 Capsule is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant, or are planning a pregnancy.

Can this medicine be taken while breast-feeding?

ETHZOLE-100 Capsule may be excreted in breast milk in a trace amount. Kindly consult your doctor before taking this medicine.

Allergy

Avoid taking ETHRAZOLE- 100 Capsule  if you are allergic to Itraconazole or any other components present in the medicine. Seek immediate medical attention if you have symptoms such as skin rashes,  itching/swelling (especially of the face/tongue/lips/throat), shortness of breath, etc.

QT interval prolongation

ETHRAZOLE- 100 Capsule may cause a problem in your heart rhythm called prolonged QT intervals (an electrical heartbeat disturbance), especially if you are taking it along with your heart medications. It may result in fast, rapid, and irregular heartbeats. Consult your doctor for further guidance in such conditions.

Congestive Heart Failure

Do not take ETHZOLE-100 Capsule if you have a history of pre-existing congestive heart failure (a condition in which the heart is unable to pump blood efficiently) or other severe heart conditions as prolonged therapy with itraconazole may worsen your condition.

Warnings for special population

Pregnancy

ETHRAZOLE- 100 Capsule is not recommended for use in pregnancy, especially during the first trimester. Consult your doctor if you are pregnant, or are planning a pregnancy.

Breast-feeding

ETHRAZOLE- 100 Capsule may be excreted in breast milk in a trace amount. Kindly consult your doctor before taking this medicine.

General warnings

Liver diseases

ETHRAZOLE- 100 Capsule can cause moderate to severe side effects on your liver, and in a rare case, it may result in serious liver toxicity. If you have a history of liver problems, inform your doctor beforehand.

Hearing loss

Quinidine is a medicine used to treat irregular heartbeats. The use of ETHRAZOLE- 100 Capsule along with Quinidine may result in temporary or permanent hearing loss. When the treatment is discontinued after your doctor's advice, hearing loss usually resolves, but consult your doctor if it persists.

Driving or operating a machine

Therapy with ETHRAZOLE- 100 Capsule may cause dizziness, confusion, or disorientation in some cases. Hence, avoid activities such as driving vehicles or operating machines if you experience any of these symptoms.

Immunocompromised patients

If you have a weak or compromised immunity [e.g., in neutropenia (low level of white blood cells), AIDS (acquired immunodeficiency syndrome) or after organ transplantation], ETHRAZOLE- 100 Capsule may not be effective enough to treat the infection. Consult your doctor for further guidance in this regard.

Neuropathy

Neuropathy is a condition where there is destruction or dysfunction of one or more nerves, resulting in numbness, muscular weakness, tingling, and pain in the affected region. If you experience these symptoms while taking ETHRAZOLE- 100 Capsule, inform your doctor immediately. Discontinue the treatment only on your doctor’s recommendation.

Women of child bearing age

Women of childbearing age should use contraceptive precautions while taking ETHRAZOLE- 100 Capsule. Continue the use of contraceptives until the next menstrual cycle even after stopping the treatment.

Missed Dose

If you forget to take a dose of ETHRAZOLE- 100 Capsule, make sure that you take it as soon as you remember. However, do not take two doses together to make up for a forgotten dose.

Overdose

Never take more than the prescribed dose. If you suspect that you might have taken an overdose of ETHRAZOLE- 100 Capsule, seek immediate medical guidance.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

• Alprazolam
• Erythromycin
• Warfarin
• Atorvastatin

Disease interactions

Liver Disease

ETHRAZOLE- 100 Capsule  should be taken with caution if you have liver problems. This medicine is mostly metabolized in the liver, so you will be advised to monitor your liver function regularly.

Achlorhydria

Achlorhydria is a disorder in which your stomach fails to produce hydrochloric acid, a component of the stomach acid that is required for digestion. The absorption of ETHRAZOLE- 100 Capsule decreases when stomach acid is decreased. Take this medicine with caution if you are diagnosed with such conditions.

Food interactions

Take ETHRAZOLE- 100 Capsule with food as it helps to increase absorption from the stomach thereby giving better efficacy.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

ETHRAZOLE- 100 Capsule should be taken orally with food exactly as prescribed by your doctor.

Do not open, chew, or crush the capsule.

Do not exceed the recommended dose.

Take the medication at the same time every day.

Antacid delays the absorption of this medicine hence, do not take antacids (stomach acid-reducing medicines) within two hours after taking ETHRAZOLE- 100 Capsule.

If you notice any side effects, report them to your doctor as soon as possible.

Your doctor may advise for some liver function tests before starting the treatment with ETHRAZOLE- 100 Capsule. If you observe any of the following symptoms like yellowing of the eyes or skin, black urine, or stomach discomfort, inform your doctor.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

ETHRAZOLE- 100 Capsule works by stopping a chemical known as ergosterol, which is responsible for the formation of fungal cell membrane. Thus, by stopping this mechanism this medicine stops the growth and spread of fungal infection.

Classification

Category

Azole antifungals

Schedule

Schedule H

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https://www.medicines.org.uk/emc/medicine/32181>

Drugs, H., 2021. Itraconazole: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 1 March 2021].

https://medlineplus.gov/druginfo/meds/a692049.html>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 1 March 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020083s040s041s044lbl.pdf>