ETHROFLOX™ PLUS Ointments

15 GM LEMI TUBE

ETHROFLOX™ PLUS Ointments is a broad-spectrum antimicrobial and anti-inflammatory topical preparation designed to treat mixed bacterial, fungal, and inflammatory skin infections. Combining the actions of an antibiotic (ofloxacin), antiprotozoal (ornidazole), antifungal (itraconazole), and a potent corticosteroid (clobetasol propionate), it offers a synergistic approach to managing complicated dermal infections with inflammatory components.

Common side effects may include:

• Burning or stinging at the application site

• Dryness, redness, or itching

• Skin thinning (prolonged use)

• Telangiectasia (spider veins) with long-term corticosteroid use

• Allergic skin reactions (rash, swelling)

• Rare: skin atrophy, striae (stretch marks), hypopigmentation

• Clean and dry the affected area before application.

• Apply a thin layer of ETHROFLOX™ PLUS Ointments over the affected area 1–2 times daily or as directed by the physician.

• Do not cover with occlusive dressings unless advised.

• Wash hands thoroughly after use.

• Avoid use on the face for long durations.

• Not recommended for use in children under 12 without medical advice.

• Prolonged use may lead to resistance or steroid-induced skin damage.

• Do not apply near eyes, mouth, or mucous membranes.

• Known hypersensitivity to any of the components

• Viral skin infections (herpes, varicella)

• Tuberculous or syphilitic skin lesions

• Acne vulgaris, rosacea, perioral dermatitis

• Open wounds or ulcerative skin conditions without physician supervision

ETHROFLOX™ PLUS Ointments For external use only; avoid ingestion or contact with eyes.

• Do not use for longer than prescribed to avoid skin damage.

• Use caution in pregnant or breastfeeding women; consult a doctor.

• Avoid abrupt discontinuation after prolonged use—taper under medical advice.

• Apply thinly over affected area once or twice daily depending on severity, or as prescribed.

• Duration: Generally, 7–14 days; prolonged use only under medical supervision.

ETHROFLOX™ PLUS OintmentsAvoid combining with other topical corticosteroids or antifungals without doctor’s advice.

• Systemic absorption is minimal, but caution is advised in patients on systemic corticosteroids, antifungals, or quinolone antibiotics.

• Use exactly as prescribed; do not increase frequency or duration.

• Do not share the medication with others.

• Complete the prescribed course even if symptoms improve early.

• If irritation or allergy occurs, discontinue and consult a physician.

• Store in a cool, dry place away from direct sunlight.

Packaging: Tube of 15 g 
Storage: Store below 25°C. Do not freeze.
Shelf Life: 24 months from the date of manufacture
Category: Prescription (Rx) topical antimicrobial-corticosteroid combination

• Indian Dermatology Guidelines on Topical Antimicrobial Combinations

• Product monographs and prescribing information for Ofloxacin, Ornidazole, Itraconazole, Clobetasol Propionate

• Textbook of Dermatology, Rook’s, 9th Edition

• British National Formulary (BNF)

• WHO Guidelines on Rational Use of Medicines