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DICLTHIX-PLUS TABLETS (A)

Diclofenac Potassium 50 mg & Paracetamol 325 mg Tablets

PACKING SIZE / TYPE

10x2x10 Blister Pack Amber PVC

Summary

DICLTHIX-PLUS TABLETS is a combination of Diclofenac and Paracetamol. It is used to reduce pain due to various conditions such as headache, toothache, backache, menstrual pain, sprains, and strains.

DICLTHIX-PLUS TABLETS also provides effective relief from pain, stiffness, and swelling due to ankylosing spondylitis (pain due to fusing of bones in the spine), osteoarthritis (pain on movement due to wearing of the protective covering at the ends of the bones) and rheumatoid arthritis (a type of arthritis where the body's immunity attacks the small joints and damages it). This medicine blocks the release of a chemical that causes pain and swelling, thus relieving these symptoms.

DICLTHIX-PLUS TABLETS causes side effects like nausea, vomiting, heartburn, stomach pain, loss of appetite, and diarrhoea. Avoid this medicine if you are allergic to it. In some patients, this medicine may cause dizziness and drowsiness. Therefore, avoid driving or operating machines if you feel drowsy or dizzy after taking this medicine.

DICLTHIX-PLUS TABLETS can be taken with food, milk, or an antacid (that your doctor may prescribe) to avoid stomach irritation. For the ease of remembering, take it at around the same time every day. Dan P Tablet relieves pain and swelling due to arthritic conditions but does not cure it. Do not self-medicate or use it beyond the prescribed duration.

DICLTHIX-PLUS TABLETS has to be used with caution if you have a history of stomach or intestinal bleeding, heart problems, asthma, and severe liver and kidney problems. Inform your doctor if you have a history of medical conditions and any medications that you may be taking. This medicine may affect the development of your foetus. Consult your doctor if you are pregnant, planning a pregnancy or are breastfeeding.

Side Effects

Major & minor side effects for DICLTHIX-PLUS TABLETS

  • Stomach pain
  • Constipation
  • Diarrhoea
  • Nausea and vomiting
  • Skin rash
  • Ringing in ears
  • Stomach or mouth ulcer
  • Bloody and cloudy urine
  • Fatigue
  • Unusual bleeding or bruising
  • Heart burn

Usage

What is it prescribed for?

Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a type of arthritis that primarily affects the spine and causes some of the small bones in the spine to fuse. AS begins in the lower back spine and can increase up to the neck. DICLTHIX-PLUS TABLETS is used to relieve stiffness and pain (especially in the lower back, hip, and pelvis) associated with ankylosing spondylitis.

Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a condition when your body's immune system attacks the lining of your small joints and also affect other parts of the body. RA is a form of arthritis where the same joints on both sides of the body are affected. DICLTHIX-PLUS TABLETS is used to relieve swelling and pain in the joints due to RA.

Osteoarthritis

Osteoarthritis (OA) is the most common form of arthritis. When a joint develops OA, the cartilage (protective tissue at the ends of the bones) breaks down, so the bones begin to rub against one another. This causes pain, stiffness, and difficulty in walking, standing or performing other activities. DICLTHIX-PLUS TABLETS is used to relieve pain and stiffness due to OA.

Dysmenorrhoea

Dysmenorrhoea (painful periods) is a throbbing, aching cramp or pain that you get in your lower belly just before and during your periods. DICLTHIX-PLUS TABLETS is used for the treatment of cramps and pain during periods.

Mild to Moderate pain

DICLTHIX-PLUS TABLETS provides relief from headache, backache, toothache, sprain, and strain.

Concerns

How long does it take for this medicine to take effect?

DICLTHIX-PLUS TAB provides relief from your aches or cramps and makes you feel better in 15-30 minutes after taking it orally.

How long do the effects of this medicine last?

The effect of DICLTHIX-PLUS TAB lasts for an average duration of 10-12 hours.

Is it safe to consume alcohol while taking this medicine?

Consumption of alcohol is not recommended while taking DICLTHIX-PLUS TAB since it may increase the risk of side effects like confusion, dizziness, and impaired judgment, and stomach bleeding.

Is this a habit forming medicine?

No habit-forming tendencies were reported for DICLTHIX-PLUS TAB.

Can this medicine be taken during pregnancy?

DICLTHIX-PLUS TAB is not recommended during pregnancy due to the risk of harmful effects on your foetus. Inform your doctor if you are pregnant while taking it. Use this medicine in pregnancy only if your doctor prescribes it.

Can this medicine be taken while breast-feeding?

DICLTHIX-PLUS TAB is not recommended for use in breastfeeding women. If required it should only be used upon your doctor's recommendation.

When not to use?

Allergy

Avoid taking DICLTHIX-PLUS TAB if you are allergic to it. Seek immediate medical attention if you notice any symptoms such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulty, etc.

Kidney failure

DICLTHIX-PLUS TAB is not recommended for use in people having severe kidney problems associated with the excessive use of painkillers. If you have pre-existing kidney problems, consult your doctor before taking the medicine.

Severe liver impairment

DICLTHIX-PLUS TAB is absorbed and broken down and absorbed in your liver. This medicine is not recommended if you already have severe liver problems as it may cause further damage to your liver.

Stomach and intestinal bleeding

DICLTHIX-PLUS TAB is not recommended for use if you have stomach ulcers or stomach and intestinal bleeding as it may worsen your condition.

Coronary Artery Bypass Surgery (CABG)

Coronary Artery Bypass Surgery (CABG) is a surgical procedure to restore normal blood flow to the heart. Do not use DICLTHIX-PLUS TAB to relieve pain after heart surgery as it may cause serious side effects.

Warnings

Warnings for special population

Pregnancy

DICLTHIX-PLUS TABLETS is not recommended during pregnancy due to the risk of harmful effects on your foetus. Inform your doctor if you are pregnant while taking it. Use this medicine in pregnancy only if your doctor prescribes it.

Breast-feeding

DICLTHIX-PLUS TABLETS is not recommended for use in breastfeeding women. If required it should only be used upon your doctor's recommendation.

General warnings

Skin rash

DICLTHIX-PLUS TABLETS may cause serious skin allergies without any warnings. Immediately report any signs and symptoms like rashes, hives (painful eruptions that itch and sting), or other allergic symptoms. Discontinue the treatment and seek further guidance from your doctor.

Water retention and oedema

DICLTHIX-PLUS TABLETS may cause oedema (accumulation of water and fluids in your body's tissue) in some people. This medicine has to be taken with caution if you have any medical condition related to your heart and kidney, high blood pressure or if you are taking any other medicines that may affect your kidney. Your blood pressure, electrolyte levels, and heart and kidney function will be closely monitored by your doctor.

Liver disease

DICLTHIX-PLUS TABLETS is broken down and absorbed in your liver. If you have pre-existing liver troubles, inform your doctor about them before taking this medicine as it can cause further damage to your liver.

Driving or operating a machine

DICLTHIX-PLUS TABLETS may cause sleepiness, blurred vision or dizziness in some people. If you experience such side effects, do not drive vehicles and operate machines after taking this medicine.

Kidney disease

DICLTHIX-PLUS TABLETS should be used with caution if you have kidney problems. Inform your doctor about your condition before taking this medicine.

Dosage

Missed Dose

If you have forgotten to take DICLTHIX-PLUS TABLETS at a scheduled time, take it as soon as you remember. However, if it is time for your next dose, skip the dose. Do not double the dose.

Overdose

Never take more than the prescribed dose. Contact your doctor in case you suspect an overdose of Reactin Plus Tablet.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Consumption of alcohol is not recommended while taking DICLTHIX-PLUS TAB since it may increase the risk of side effects like confusion, dizziness, and impaired judgment, and stomach bleeding.

Interaction with Medicine

  • Carbamazepine
  • Methotrexate
  • Phenytoin
  • Ramipril
  • Sodium Nitrite
  • Apixaban
  • Aspirin

Disease interactions

Asthma

Asthma is an allergic reaction causing narrowing and excess mucous secretion in the air pathway of your lungs leading to breathing difficulty. People with asthma may experience allergic reactions or the triggering of an asthmatic attack while taking DICLTHIX-PLUS TAB. Hence, it is not recommended for use in people with asthma, especially those who have a history of allergic reactions with the use of non-steroidal anti-inflammatory medicines (a type of painkillers).

Heart disease

Long-term use of DICLTHIX-PLUS TAB may increase the risk of a heart attack in patients with pre-existing heart conditions or heart failure. It should not be used to treat pain after a coronary bypass surgery.

Gastro-Intestinal toxicity

Long term use of DICLTHIX-PLUS TAB can cause damage to the stomach and intestine. Serious conditions like bleeding, ulceration and a hole in the linings of the stomach or intestinal wall may occur.  If you experience chronic indigestion, the appearance of coffee coloured dry blood in stools or vomiting of blood, contact your doctor immediately as these symptoms are suggestive of gastrointestinal bleeding and ulceration.

Food interactions

Information not available.

Lab interactions

5-HIAA Urine Test

DICLTHIX-PLUS TAB can interfere with a urine test and may give a false-positive result. It is advised to inform your doctor and lab technician about all your current medicines before undergoing any lab test.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

General Instructions

Take DICLTHIX-PLUS TABLETS with or after food to avoid stomach upset. Do not break, crush or chew the tablet.

Avoid self-medication and never take more than the prescribed dose. Never take this medicine for more than the prescribed duration.

Take DICLTHIX-PLUS TABLETS at around the same time daily.

Avoid alcohol consumption while taking this medicine as it may elevate dizziness or drowsiness and stomach bleeding.

Do not drive or operate machines if you feel dizzy or drowsy.

Other Details

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

DICLTHIX-PLUS TABLETS stops the release of a chemical called prostaglandins, which increases pain and swelling. Thus, this medicine provides pain relief and makes you feel better.

Classification

Category

Nonsteroidal anti-inflammatory agents, Analgesics

Schedule

Schedule H

References

Pubchem.ncbi.nlm.nih.gov. 2021. Acetaminophen. [online] Available at: < [Accessed 22 April 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/1983>

Pubchem.ncbi.nlm.nih.gov. 2021. Diclofenac. [online] Available at: < [Accessed 17 May 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/Diclofenac>

Drugs, H., 2021. Acetaminophen: MedlinePlus Drug Information. [online] Medlineplus.gov. Available at: < [Accessed 27 July 2021].

https://medlineplus.gov/druginfo/meds/a681004.html>

Medicines.org.uk. 2021. Diclofenac Sodium 50mg Gastro-Resistant Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 27 July 2021].

https://www.medicines.org.uk/emc/product/2660>

Fdaghana.gov.gh. 2021. [online] Available at: < [Accessed 28 July 2021].

https://fdaghana.gov.gh/img/pils/Pedol%20Tablets%20(Paracetamol%20and%20Diclofenac%20Sodium).p