C3FETHIX-SB 1.5

5 ML

C3FETHIX-SB  1.5 g Injection is a combination of medicines cefoperazone and sulbactam. It is an antibiotic used to treat infections of the respiratory tract (organs involved in breathing), urinary tract (organs that make urine and remove it from the body), bones, joints, and skin and soft tissue, etc. This medicine works by preventing the formation of the bacterial cell wall which is important for the growth of bacteria.

C3FETHIX-SB  1.5 g Injection shows side effects like nausea, vomiting, diarrhoea, anaemia (low number of red blood cells), etc. C3FETHIX-SB  1.5 g Injection should only be administered by a qualified doctor or nurse. Make sure to take the complete course of this medicine, even if you feel better.

C3FETHIX-SB  1.5 g Injection is not recommended if you are allergic to Cefoperazone or Sulbactam. Inform your doctor if you have any problems related to the kidney, liver, or heart. If you are taking any medicines or herbal supplements inform your doctor before starting treatment with this medicine. If you are pregnant or breastfeeding, consult with your doctor before going through the treatment with C3FETHIX-SB  1.5 g Injection.

Major & minor side effects for Cefoperazone & Sulbactam for Injection 1.5 g Injection

• Headache
• Nausea and Vomiting
• Diarrhoea
• Rash
• Itching
• Blood in urine
• Decrease in blood cell count
• Gastrointestinal side effects
• Chills
• Injection site pain

What is it prescribed for?

• Urinary tract infections

Urinary tract infections (UTI) are infections of organs that are involved in the production of urine and its removal from the body. These organs include the kidneys, bladder, and urethra. The symptoms of UTI are pain during urination, blood in urine and lower abdominal pain.C3FETHIX-SB 1.5 g Injection is used in the treatment of urinary tract infections caused by bacteria such as Escherichia coli, Pseudomonas aeruginosa, etc.

• Respiratory Tract Infection

C3FETHIX-SB 1.5 g Injection is used in the treatment of your upper and lower respiratory tract infections caused by bacteria such as Staphylococcus aureus, Escherichia coli, Klebsiella species, Proteus mirabilis, Enterobacter species, etc.

• Intra-abdominal Infection

Intra-abdominal Infection is an infection within your abdomen. It includes peritonitis (swelling in the lining of your abdominal wall), cholecystitis (swelling of your gall bladder), and cholangitis (swelling of the bile duct, the duct that carries bile from liver to small intestine) caused by bacteria such as Escherichia coli, Pseudomonas aeruginosa, etc. C3FETHIX-SB 1.5 g Injection is used in the treatment of this condition.

• Bacterial Septicaemia

Bacterial septicaemia is an infection in your blood that may be caused by bacteria such as Pseudomonas aeruginosa, Haemophilus influenzae, Escherichia coli, etc. If left untreated this infection can be life-threatening. C3FETHIX-SB 1.5 g Injection is used to treat such conditions by preventing the growth and spread of bacteria.

• Skin and Soft tissue infections

C3FETHIX-SB 1.5 g Injection is used in the treatment of skin and soft tissue infections caused by bacteria such as Staphylococcus aureus, Streptococcus pyogenes, Pseudomonas aeruginosa, etc. It prevents the growth and spread of bacteria by stopping the development of bacterial cell walls which is necessary for bacterial growth.

• Gynaecologic infections

C3FETHIX-SB 1.5 g Injection is used in the treatment of your gynecologic infections such as endometritis (swelling in the lining of the uterus), pelvic inflammatory disease (an infection of the female reproductive organs), gonorrhoea (sexually transmitted bacterial disease), etc. caused by bacteria such as Neisseria gonorrhoeae, Staphylococcus epidermidis, Streptococcus agalactiae, Escherichia coli, etc. The medicine prevents the spread of bacteria by stopping the formation of bacterial cell walls which is necessary for their growth.

Commonly asked questions

• How long does it take for this medicine to take effect?

The effect of C3FETHIX-SB 1.5 g Injection can be observed rapidly after an intravenous or intramuscular administration.

• How long do the effects of this medicine last?

The amount of time for which C3FETHIX-SB 1.5 g Injection remains active in the body is not clinically established.

• Is it safe to consume alcohol while taking this medicine?

Avoid using C3FETHIX-SB 1.5 g Injection along with alcohol as it may cause disulfiram like-reaction. This reaction is characterized by symptoms such as severe vomiting, pain in your stomach, headache, irregular heartbeat, difficulty in breathing, sweating, etc. Inform your doctor if you experience any such symptoms.

• Is this a habit forming medicine?

No habit-forming tendencies were reported for C3FETHIX-SB 1.5 g Injection.

• Can this medicine be taken during pregnancy?

C3FETHIX-SB 1.5 g Injection is considered to be safe during pregnancy. According to some research, this medicine does not harm the unborn baby. However, if you are pregnant talk to your doctor about the potential risks and benefits before taking this medicine.

• Can this medicine be taken while breast-feeding?

C3FETHIX-SB 1.5 g Injection is considered safe during breastfeeding. The medicine does not pass into breast milk. However, if you are breastfeeding, talk to your doctor about the potential risks and benefits before taking this medicine.

Allergy

Avoid receiving C3FETHIX-SB 1.5 g Injection if you are allergic to Cefoperazone or sulbactam. Seek immediate medical attention if you notice any symptoms of allergic reactions such as skin rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, breathing difficulties, etc.

Warnings for special population

Pregnancy

C3FETHIX-SB 1.5 g Injection is considered to be safe during pregnancy. According to some research, this medicine does not harm the unborn baby. However, if you are pregnant talk to your doctor about the potential risks and benefits before taking this medicine.

Breast-feeding

C3FETHIX-SB 1.5 g Injection is considered safe during breastfeeding. The medicine does not pass into breast milk. However, if you are breastfeeding, talk to your doctor about the potential risks and benefits before taking this medicine.

General warnings

Kidney impairment

C3FETHIX-SB 1.5 g Injection should be used with caution if you have a history of kidney problems. This medicine is excreted through the kidney, and any impairment in kidney function may lead to its accumulation in the body, resulting in an increased risk of side effects.

Drug resistance

Avoid using C3FETHIX-SB 1.5 g Injection without your doctor's prescription. Your doctor may prescribe antibiotics based on the bacteria causing the infection and if the medicine is used for the wrong bacterial infection it may cause antibiotic resistance.

Diarrhoea

C3FETHIX-SB 1.5 g Injection may kill gut-friendly bacteria which may promote the growth of an undesired bacteria called Clostridium difficile, resulting in diarrhoea. Consult your doctor for dose adjustment or replacement.

Liver diseases

C3FETHIX-SB 1.5 g Injection should be used with extreme caution if you have a history of liver problems or active liver problems as it can increase the risk of serious side effects. Close monitoring of liver function might be required while you take this injection.

Missed Dose

Since C3FETHIX-SB 1.5 g Injection is administered by a qualified healthcare professional in the clinical or hospital setting, the likelihood of a missed dose is very low.

Overdose

Since C3FETHIX-SB 1.5 g Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of an overdose is very low. However, emergency medical treatment will be initiated by your doctor if an overdose is suspected.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

Avoid using C3FETHIX-SB 1.5 g Injection along with alcohol as it may cause disulfiram like-reaction. This reaction is characterized by symptoms such as severe vomiting, pain in your stomach, headache, irregular heartbeat, difficulty in breathing, sweating, etc. Inform your doctor if you experience any such symptoms.

Interaction with Medicine

Live cholera vaccine

Furosemide

Typhoid vaccine live

BCG vaccine live

Disease interactions

Disease

Information not available.

Food interactions

Information not available.

Lab interactions

Benedict's or Fehling's Test

Benedict's or Fehling's Test is used to test the sugar levels in urine. Avoid taking C3FETHIX-SB 1.5 g Injection as it may give a false-positive result for the presence of sugar in your urine.

Coomb's test

Avoid use of C3FETHIX-SB 1.5 g Injection as it may give a false-positive result for the Coombs test. This test is used to detect anaemia caused by the excessive destruction of your red blood cells. An alternative test may be used during treatment with this medicine.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

C3FETHIX-SB 1.5 g Injection should be administered by a qualified healthcare professional in the clinical or hospital setting. Inform the doctor if you have a known history of allergy to this medicine. Before taking this medicine, inform your doctor about all of your current medications. Consult your doctor immediately if you experience any severe side effects after taking this medicine.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

C3FETHIX-SB 1.5 g Injection contains Cefoperazone and sulbactam. Cefoperazone interferes with bacterial cell wall formation which stops their growth. Whereas; sulbactam works by improving the effectiveness of Cefoperazone against bacteria.

Legal Status

Approved

Unknown

Unknown

Unknown

Classification

Category

Beta-lactamase inhibitors, Third generation cephalosporins

Schedule

Schedule H

CiplaMed. 2021. ZOSUL Injection. [online] Available at: < [Accessed 6 July 2021].

https://www.ciplamed.com/content/zosul-injection>

Pubchem.ncbi.nlm.nih.gov. 2021. Sulbactam. [online] Available at: < [Accessed 6 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/130313>

Pubchem.ncbi.nlm.nih.gov. 2021. Cefoperazone. [online] Available at: < [Accessed 6 July 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/44187>