PARNZOLEIX-IV INJECTION

10 ml with Carton

PARNZOLEIX 40 MG INJECTION is a medicine that contains pantoprazole. It is used to treat conditions caused due to excess40 mge acid production in your stomach. Stomach and duodenal ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome are certain conditions associated with high levels of stomach acid. PARNZOLEIX 40 MG INJECTION helps in the treatment of act40 mge gastric (stomach) or duodenal (small intestine) ulcers with bleeding or severe erosions. PARNZOLEIX 40 MG INJECTION interferes with the final step of acid release in the stomach. Thus, acidity in the stomach is decreased and the ulcer healing process is fastened. Common side effects of PARNZOLEIX 40 MG INJECTION are headache, pain, redness and swelling at the injection site, diarrhoea, and dizziness. these effects are generally mild and subside with time, consult your doctor if any of these symptoms persist for a long time. Do not take this medicine if you are allergic to it. PARNZOLEIX 40 MG INJECTION is administered into your vein by a health care professional in a hospital or clinic. PARNZOLEIX 40 MG INJECTION is recommended for people with oesophagus damage (the tube that carries food from the throat to the stomach) or who are unable to take oral forms of pantoprazole. You should avoid spicy and fatty foods, alcohol and caffeine-containing beverages such as coffee, tea and cola if you have acid-related conditions. Eating a healthy and balanced diet will help you to heal faster. Always try to finish your dinner three hours before heading to bed.

Major & minor side effects for PARNZOLEIX 40 mg Injection

• Headache
• Altered sense of taste
• Fast or slow or irregular heartbeat
• Diarrhoea
• Muscle pain
• Unusual tiredness and weakness
• Loss of appetite
• Injection site pain
• Nausea and vomiting

What is it prescribed for?

Erosive Esophagitis

Oesophagitis is the swelling of the oesophagus, the muscular tube that carries food from the throat to the stomach. It occurs when excess acid produced in the stomach flows back into the oesophagus. It can also be caused due to an infection or irritation in the oesophagus. All these reasons can irritate and damage the lining of the oesophagus, resulting in a condition called erosive oesophagitis. PARNZOLEIX 40 mg Injection is used to treat erosive oesophagitis caused by stomach acid production.

Gastroesophagal Reflux Disease

Gastroesophageal Reflux Disease (GERD) is an acid reflux disease that occurs when stomach acid frequently flows back into the oesophagus or food pipe causing heartburn(burning sensation above the stomach) and acid indigestion. This condition can be managed with diet, lifestyle changes and over-the-counter medications to an extent. Sometimes surgery is needed to get rid of this condition. PARNZOLEIX 40 mg Injection helps in the short-term treatment of GERD by decreasing stomach acid production.

Zollinger-Ellison Syndrome

Zollinger-Ellison Syndrome is a condition in which tumours form in the pancreas or duodenum (the first part of the small intestine). These tumours produce a hormone called gastrin which in turn causes excessive stomach acid. PARNZOLEIX 40 mg Injection is used to treat this condition by reducing the excessive secretion of gastrin.

How long does it take for this medicine to take effect?

PARNZOLEIX 40 mg Injection produces its maximum effects within 2-6 hours of administration.

How long do the effects of this medicine last?

The duration of action for PARNZOLEIX 40 mg Injection is about 24 hours.

Is it safe to consume alcohol while taking this medicine?

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Is this a habit forming medicine?

No habit-forming tendencies were reported for PARNZOLEIX 40 mg Injection.

Can this medicine be taken during pregnancy?

PARNZOLEIX 40 mg Injection is usually not recommended if you are pregnant. It may harm your foetus. However, your doctor may prescribe this medicine if the benefits outweigh the risks.

Can this medicine be taken while breast-feeding?

PARNZOLEIX 40 mg Injection may pass into breast milk and may harm your infant. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. However, your doctor may prescribe this medicine if the benefits outweigh the risks.

Allergy

Avoid receiving PARNZOLEIX 40 mg Injection if you are allergic to it. Allergic reactions are very rare. Seek immediate medical attention if you notice any allergic symptoms like skin rash, itching/swelling of the face/tongue/throat, breathing difficulties, etc

Warnings for special population

Pregnancy

PARNZOLEIX 40 mg Injection is usually not recommended if you are pregnant. It may harm your foetus. However, your doctor may prescribe this medicine if the benefits outweigh the risks.

Breast-feeding

PARNZOLEIX 40 mg Injection may pass into breast milk and may harm your infant. An alternate medicine may be preferred, especially while nursing a newborn or preterm infant. However, your doctor may prescribe this medicine if the benefits outweigh the risks.

General warnings

Bone fractures

Long term use of PARNZOLEIX 40 mg Injection decreases the calcium absorption in your body leading to reduced bone density (thinning of bones). Calcium is essential for bone formation and its deficiency can increase the risk of bone fractures. Take calcium supplements or increase the intake of calcium in your diet to avoid bone thinning. Using Vitamin D supplements along with PARNZOLEIX 40 mg Injection can help to increase calcium absorption in your body.

Lupus erythematosus

Lupus erythematosus is an autoimmune disease that affects the skin, kidneys, brain, joints, and other organs. It occurs when your immune system attacks its own tissues. Lupus may occur or gets worse while using PARNZOLEIX 40 mg Injection. Inform your doctor immediately if you experience tiredness, painful joints, rashes, or lesions on the skin while using this medicine.

Hypomagnesemia

Prolonged use of PARNZOLEIX 40 mg Injection may result in a reduction of magnesium levels in your blood (hypomagnesemia). Inform your doctor in case of dizziness, irregular heartbeat, shivering, muscle pain, seizures or fits. You may have to check magnesium levels in the blood at regular intervals.

Missed Dose

Since PARNZOLEIX 40 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the likelihood of a missed dose is very low.

Overdose

Since PARNZOLEIX 40 mg Injection is administered in the hospital or clinical setting by a qualified healthcare professional, the chances of an overdose are very low. However, emergency medical treatment will be initiated by the doctor if an overdose is suspected.

Interactions

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Instructions

Interaction with alcohol is unknown. It is advisable to consult your doctor before consumption.

Interaction with Medicine

Methotrexate

Warfarin

Nelfinavir

Digoxin

Disease interactions

Liver Disease

People with liver problems need special consideration while taking PARNZOLEIX 40 mg Injection due to the risk of worsening of the condition. Dose adjustment may be needed.

Osteoporosis

Osteoporosis is a condition in which bones become weak and fragile. Long term use of PARNZOLEIX 40 mg Injection can reduce bone density (thinning of bones). PARNZOLEIX 40 mg Injection decreases the calcium absorption in the body leading to calcium deficiency. This can increase the risk of bone fractures, especially in osteoporosis conditions. Take calcium supplements or increase the intake of calcium in your diet to avoid bone thinning. Using Vitamin D supplements along with PARNZOLEIX 40 mg Injection can help to increase calcium absorption in your body.

Colitis

PARNZOLEIX 40 mg Injection may cause diarrhoea. Take it with extreme caution if you have any gastrointestinal problems, particularly colitis (swelling of the inner lining of the colon), since it may cause severe diarrhoea.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

PARNZOLEIX 40 mg Injection should be administered by a qualified healthcare professional in the clinical or hospital setting. Report any undesirable side effects to the doctor promptly. You may observe a small bump at the injection site which is normal. Calcium supplements may be advised to prevent bone weakening.

Miscelleneous

Usage does not depend on food timings

To be taken as instructed by doctor

Does not cause sleepiness

How it works

PARNZOLEIX 40 mg Injection reduces the production of stomach acid. It stops the action of the proton pumps that are found on cells that line the stomach, thus decreases stomach acid production.

Classification

Category

Proton pump inhibitors

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Pantoprazole. [online] Available at: < [Accessed 9 August 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/4679>

Dailymed.nlm.nih.gov. 2021. These highlights do not include all the information needed to use PARNZOLEIX IV INJECTION. safely and effectively. See full prescribing information for PARNZOLEIX IV INJECTION. (pantoprazole sodium) for injection, for intravenous useInitial U.S. approval: 2000. [online] Available at: < [Accessed 9 August 2021].

https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=48f4d638-d2a1-47fa-9a81-3acda1b1b1e3>

Medicines.org.uk. 2021. [online] Available at: < [Accessed 9 August 2021].

https://www.medicines.org.uk/emc/files/pil.2833.pdf>

Accessdata.fda.gov. 2021. [online] Available at: < [Accessed 17 August 2021].

https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020988s052lbl.pdf>