Glizora™-80 Tablets

10X10 Tablets

Glizora™-80 Tablets is an anti-diabetic medicine used in the treatment of type 2 Diabetes mellitus (high levels of sugar in the blood). It helps in controlling blood sugar levels and prevents complications of diabetes such as blindness, kidney damage, stroke (reduced blood supply to your brain), and heart attack. The medicine helps in the production of insulin (a hormone that regulates sugar levels in your blood), which reduces the excess blood sugar levels in your body.

Glizora™-80 Tablets shows side effects like indigestion and upset stomach. This medicine can occasionally cause low blood sugar levels, the signs being sweating, dizziness, and shivering. To avoid these side effects, eat your meals on time and carry a sugar source (sweets or fruit juice) for immediate relief. Avoid using this medicine if you are allergic to it. Alcohol should be avoided while using this medicine as it can lower your blood glucose levels.

Glizora™-80 Tablets is recommended to be taken 30 minutes before breakfast. Do not chew or crush the tablet. Take Glizora™-80 Tablets as per the prescription. For the ease of remembering, take this tablet around the same time every day. Do not stop taking this medicine unless advised by your doctor, even if your sugar levels are normal.

Glizora™-80 Tablets should not be taken if you have type 1 diabetes (a condition where your body is unable to produce insulin, hence you have to take insulin injections), diabetic ketoacidosis (high amounts of acid in your blood) or severe kidney or liver problems. Inform your doctor about any history of heart problems before taking this medication. If you are pregnant or are breastfeeding, inform your doctor before taking this medicine.

Major & minor side effects for Glizora™-80 Tablets

• Dizziness
• Nausea or vomiting
• Confusion
• Weakness
• Sweating
• Changes in vision
• Decreased heartbeat
• Stomach pain
• Constipation
• Skin rash
• Elevated liver enzymes
• Low blood sugar levels

What is it prescribed for?

• Type II Diabetes Mellitus

Type II Diabetes mellitus (DM) is a condition caused by excess blood sugar levels in your body. This is due to a decreased production of insulin (a hormone that regulates your blood sugar levels) and also due to decreased response of your body to insulin. Glizora™-80 Tablets is used in type II Diabetes. It works by increasing the release of insulin from your pancreas which helps in lowering your blood sugar levels.

Commonly asked questions

• How long does it take for this medicine to take effect?

The amount of time required for Glizora™-80 Tablets to show its action is 1-2 hours

• How long do the effects of this medicine last?

The effect of Glizora™-80 Tablets lasts for an average duration of 1 to 2 days.

• Is it safe to consume alcohol while taking this medicine?

You should avoid or limit the consumption of alcohol while you are on treatment with Glizora™-80 Tablets. Consumption of alcohol may increase the risk of side effects such as confusion, dizziness, nausea, vomiting, weakness, and fainting.

• Is this a habit forming medicine?

No habit forming tendencies were reported for Glizora™-80 Tablets.

• Can this medicine be taken during pregnancy?

Glizora™-80 Tablets is usually not advised during pregnancy because it might have significant side effects on your foetus. However, if you are pregnant your doctor may prescribe alternative medicine with the same medicinal effect.

• Can this medicine be taken while breast-feeding?

Avoid using Glizora™-80 Tablets if you are breastfeeding. There is no sufficient information available to know whether this medicine can pass into your breast milk. Your doctor may prescribe a safer alternative with the same medicinal effect based on your clinical condition.

Allergy

Do not take Glizora™-80 Tablets if you have any allergy to it. Inform your doctor if you experience any symptoms of allergic reactions such as skin rashes, itching/swelling (especially of your face/tongue/throat), severe dizziness or breathing difficulty etc.

Diabetic ketoacidosis

Diabetic ketoacidosis is a complication of diabetes characterized by the overproduction of ketones (blood acids) in your body. Do not take Glizora™-80 Tablets if you have diabetic ketoacidosis as it can progress to lactic acidosis (increased level of lactic acid in your blood) which is a major health concern.

Severe kidney impairment

Glizora™-80 Tablets should not be taken if you have any kidney troubles. This medicine is excreted through urine and taking this medicine while you have pre-existing kidney problems can worsen the condition of your kidneys.

Severe liver impairment

Glizora™-80 Tablets is absorbed in the liver and excreted through urine. If you have any liver problems, use this medicine with extreme caution as it may lead to accumulation and toxicity.

Warnings for special population

Pregnancy

Glizora™-80 Tablets is usually not advised during pregnancy because it might have significant side effects on your foetus. However, if you are pregnant your doctor may prescribe alternative medicine with the same medicinal effect.

Breast-feeding

Avoid using Glizora™-80 Tablets if you are breastfeeding. There is no sufficient information available to know whether this medicine can pass into your breast milk. Your doctor may prescribe a safer alternative with the same medicinal effect based on your clinical condition.

General warnings

Hypoglycemia

Hypoglycemia is a condition with decreased blood sugar levels. If you are prone to having low blood sugar level episodes, Glizora™-80 Tablets should be taken with caution. Inform your doctor about this condition. They will suggest tests to monitor your blood glucose level regularly.

Use in children

Glizora™-80 Tablets is not recommended for use in children and adolescents below 18 years of age because the safety and efficacy data is not available.

Driving or Operating machines

Glizora™-80 Tablets may occasionally reduce your blood sugar levels, which may impair your concentration and your ability to perform these activities.

Missed Dose

If you missed a dose of Glizora™-80 Tablets, take it as soon as you remember. If it is almost time for your next, skip the missed dose. Do not take two doses together to make up for a missed dose.

Overdose

Never take more than the prescribed dose of Glizora™-80 Tablets. If you suspect that you might have taken an overdose of this medicine, go to the nearest emergency medical department/hospital.

All drugs interact differently for person to person. You should check all the possible interactions with your doctor before starting any medicine.

Interaction with Alcohol

Description

N/A

Instructions

You should avoid or limit the consumption of alcohol while you are on treatment with Glizora™-80 Tablets. Consumption of alcohol may increase the risk of side effects such as confusion, dizziness, nausea, vomiting, weakness, and fainting.

Interaction with Medicine

Miconazole

Phenylbutazone

Chlorpromazine

Disease interactions

Heart Disease

If you have problems with the heart and blood vessels, use Glizora™-80 Tablets with caution as it can increase the risk of heart failure.

Type 1 diabetes mellitus

Glizora™-80 Tablets works by stimulating the pancreas to produce insulin. Therefore it should not be taken if you have Type I Insulin Dependent Diabetes (a condition where your body is unable to produce insulin, hence you have to take insulin injections).

Hemolytic Anaemia/G6PD Deficiency

Hemolytic Anaemia/G6PD Deficiency is an inherited condition that affects red blood cells, which carry oxygen from your lungs to tissues throughout your body. It occurs due to a deficiency of an enzyme called G6PD (glucose-6-phosphate dehydrogenase) that causes red blood cells to break down prematurely. Its symptoms are fever, dark urine, stomach pain, fatigue and pale skin. Glizora™-80 Tablets should be used with caution if you have hemolytic anaemia as it may worsen your condition.

Food interactions

Information not available.

Lab interactions

Information not available.

This is not an exhaustive list of possible drug interactions. You should consult your doctor about all the possible interactions of the drugs you’re taking.

Take Glizora™-80 Tablets as instructed by your doctor. Your doctor may change the dose over time based on the therapeutic response and your clinical condition. You should monitor your blood sugar levels regularly. Always carry a sugar candy with you to counteract unexpected lowering of blood sugar levels.

Miscelleneous

To be taken with food

To be taken as instructed by doctor

May cause sleepiness

How it works

Glizora™-80 Tablets works by increasing the release of insulin from your pancreas (a part of your digestive system that produces insulin and other vital enzymes). Thus it lowers your blood sugar levels.

Legal Status

Approved

Unknown

Approved

Approved

Classification

Category

Sulfonylureas

Schedule

Schedule H

Pubchem.ncbi.nlm.nih.gov. 2021. Gliclazide. [online] Available at: < [Accessed 8 June 2021].

https://pubchem.ncbi.nlm.nih.gov/compound/3475>

Medicines.org.uk. 2021. Diamicron 80mg Tablets - Summary of Product Characteristics (SmPC) - (emc). [online] Available at: < [Accessed 26 July 2021].

https://www.medicines.org.uk/emc/product/1150/smpc>