top of page

Domestic:

+91 770 788 7676 

International:

+1 647 893 7323 

ETHNEM-1GM

 Meropenem Injection 1GM I.P

PACKING SIZE / TYPE

20ML WITH CARTON

Summary

ETHNEM-1GM is a broad-spectrum carbapenem antibiotic containing Meropenem 1GM I.P. It is designed to combat a wide variety of severe bacterial infections. Its efficacy against gram-positive, gram-negative, and anaerobic bacteria makes it a versatile choice in critical care.

Side Effects

  • Common: Nausea, vomiting, headache, diarrhea, constipation
  • Serious: Allergic reactions, anaphylaxis, rash, seizures, thrombocytopenia, neutropenia
  • Rare: Kidney dysfunction, liver enzyme elevation

Usage

  • Administered intravenously by healthcare professionals.
  • Dosage and duration depend on the severity and type of infection, age, weight, and renal function.
  • Reconstitute the injection as per instructions before use.

Concerns

  • Resistance development due to misuse or overuse.
  • High costs in resource-limited settings.
  • Risk of superinfections with prolonged usage.

When not to use?

  • Known hypersensitivity to Meropenem or other carbapenems.
  • History of severe allergic reactions to beta-lactam antibiotics.
  • Not recommended for viral infections like the common cold or flu.

Warnings

  • Allergic Reactions: Monitor for signs of hypersensitivity.
  • Seizures: Use with caution in patients with a history of central nervous system disorders.
  • Renal Impairment: Dose adjustments required in patients with kidney dysfunction.
  • Pregnancy & Lactation: Use only if the potential benefit justifies the risk.
  • Drug Interactions: Avoid combining with valproic acid, as it may reduce the drug's efficacy.

Dosage

  • Adults: 500 mg to 1 gm every 8 hours, depending on infection severity.
  • Pediatrics: 20–40 mg/kg every 8 hours (maximum of 2 gm/day).
  • Dosage adjustments needed for renal impairment (creatinine clearance ≤ 50 mL/min).

Interactions

  • Valproic Acid: Decreases serum levels, reducing seizure control.
  • Probenecid: Increases meropenem levels by reducing renal clearance.
  • Anticoagulants: Monitor INR when used with warfarin.

General Instructions

  • Store in a cool, dry place (2–8°C) and protect from light.
  • Only a healthcare professional should reconstitute and administer the injection.
  • Complete the prescribed course to prevent resistance, even if symptoms improve.

Other Details

  • Brand Name: ETHNEM-1GM
  • Category: Broad-Spectrum Antibiotic
  • Formulation: Powder for injection
  • Pack Size: Vial

References

  • Clinical Guidelines on Antibiotic Use - World Health Organization (WHO).

  • Meropenem Product Information - U.S. Food and Drug Administration (FDA).

  • Pharmacological Review - Journal of Antimicrobial Chemotherapy.

bottom of page