Domestic:
+91 92 5656 7676
International:
+1 647 893 7323


ETHRAB - IT
Rabeprazole (EC) 20mg Itopride (SR)150mg Capsules
PACKING SIZE / TYPE
10x10 ALU ALU PACK
Summary
RABEPRAZOLE+ITOPRIDE is used to lower the increased level of stomach acid. It treats GERD (gastro-oesophagal reflux disease), and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach.
RABEPRAZOLE+ITOPRIDE is a combination of two drugs: Rabeprazole and Itopride. Rabeprazole is a proton pump inhibitor (PPI) that works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. It minimizes the release of acid from the stomach, which provides relief from heartburn and acid-related digestion. While Itopride works on the part of the brain that is responsible for controlling vomiting. It increases gastric emp undying improves gastric sensitivity and tension by increasing the stomach's movement and intestines in the upper digestive tract. It also has anti-emetic action. Together, RABEPRAZOLE+ITOPRIDE helps prevent acid reflux, thereby relieving acidity.
Take RABEPRAZOLE+ITOPRIDE 30-60 minutes before food. Do not chew or break the tablet; swallow it as a whole with a glass of water. You are advised to take RABEPRAZOLE+ITOPRIDE for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, nausea, stomach pain, dizziness, and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Inform your doctor before taking RABEPRAZOLE+ITOPRIDE if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. On long-term treatment, RABEPRAZOLE+ITOPRIDE may cause osteoporosis and hypomagnesemia (low levels of magnesium). Do not take RABEPRAZOLE+ITOPRIDE if you are pregnant or breastfeeding unless prescribed by the doctor. RABEPRAZOLE+ITOPRIDE causes drowsiness, so drive only if you are alert. RABEPRAZOLE+ITOPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol with RABEPRAZOLE+ITOPRIDE as it can lead to increased drowsiness and increased acid production.
Side Effects
- Nausea
- Dizziness
- Diarrhoea
- Headache
- Stomach pain
Usage
Treatment of Hyperacidity, Gastro-oesophageal reflux disease, Peptic ulcer.
Concerns
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, the mucous layer gets eroded due to excess acid production, which leads to complications like GERD, acidity, and peptic ulcers. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste, and difficulty swallowing. Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, changes in appetite, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
When not to use?
Avoid using ETHRAB-IT if:
- You are allergic to Rabeprazole, Itopride, or any excipients in the capsule.
- You have severe liver impairment.
- You are pregnant or breastfeeding, unless advised by a healthcare provider.
Warnings
Do not take RABEPRAZOLE+ITOPRIDE if you are allergic to any of its contents. Inform your doctor before taking RABEPRAZOLE+ITOPRIDE if you have a history of gastrointestinal bleeding, mechanical perforation/obstruction, or movement disorder. RABEPRAZOLE+ITOPRIDE may cause osteoporosis on long-term treatment. RABEPRAZOLE+ITOPRIDE may also cause hypomagnesemia (low magnesium). Do not take RABEPRAZOLE+ITOPRIDE if you are pregnant or breastfeeding unless prescribed by the doctor. RABEPRAZOLE+ITOPRIDE causes dizziness, so drive only if you are alert. RABEPRAZOLE+ITOPRIDE should not be given to children as safety has not been established. Avoid consuming alcohol along with RABEPRAZOLE+ITOPRIDE as it could lead to increased drowsiness and elevate stomach acid production. Keep your doctor informed about all the medicines and your health condition to rule out any side effects. Consult your doctor if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. On long-term treatment, RABEPRAZOLE+ITOPRIDE may cause osteoporosis and hypomagnesemia (low levels of magnesium), and may reduce the absorption of vitamin B12.
Dosage
- Recommended Dose: One capsule daily before meals or as prescribed by a physician.
- Do not exceed the recommended dosage without medical supervision.
Interactions
DRUG-DRUG INTERACTIONS: RABEPRAZOLE+ITOPRIDE may have interaction with pain killers (aspirin, naproxen), an antidepressant (duloxetine), hypothyroidism (levothyroxine), statins (atorvastatin), blood thinner (clopidogrel), and vitamin (vitamin b12).
FOOD-DRUG INTERACTIONS: Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
DRUG-DISEASE INTERACTION: RABEPRAZOLE+ITOPRIDE may have interactions with gastrointestinal bleeding, mechanical obstruction or perforation, Clostridium difficile-associated diarrhoea (CDAD), liver disease, bone fractures, hypomagnesemia (low levels of magnesium).
Drug-Drug Interactions Checker List:
- ASPIRIN
- NAPROXEN
- DULOXETINE
- LEVOTHYROXINE SODIUM
- ATORVASTATIN
- CLOPIDOGREL
- CYANOCOBALAMIN
General Instructions
- Take the capsule whole with water, preferably before a meal.
- Follow the prescribed dosage schedule strictly.
- Do not stop the medication abruptly without consulting your doctor.
- Store in a cool, dry place, away from direct sunlight and moisture.
Other Details
- Storage: Keep below 25°C in original packaging.
- Packaging: Available in blister packs for optimal freshness and convenience.
References
-
Clinical Pharmacology of Rabeprazole and Itopride, Journal of Gastroenterology.
-
Drug Interactions with Proton Pump Inhibitors, Pharmacological Reviews.
-
Guidelines for GERD and Dyspepsia Management, American Gastroenterological Association.